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Obstetrics & Gynecology 1976;47:69-76
© 1976 by The American College of Obstetricians and Gynecologists
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The Clinical Syndrome of Triploidy

WLADIMIR WERTELECKI, MD, JOHN M. GRAHAM, Jr., MD and FRED R. SERGOVICH, PhD

From the Department of Medical Genetics. University of South Alabama, School of Medicine. Medical University of South Carolina, and Children's Psychiatric Research Institute, London, Ontario

Abstract

The clinical syndrome associated with triploidy is quite typical but is rarely reported in near-term stillborns and new boms. The occurrence of a large placenta with areas of hydatidiform changes in combination with an edematous fetus with macroglossia, facial elefts, eye defects, dysplaslic cranial bones, omphalocele, meningomyelocele, syndactyly, and, in males, genital maldevelopment is suggestive of a triploid chromosomal constitution.




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