HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by DIMMICK, J. Articles by ALTSHULER, G. Search for Related Content PubMed PubMed Citation Articles by DIMMICK, J. Articles by ALTSHULER, G.

Antenatal Infection: Adequate Protection Against Hyaline Membrane Disease?

From the Departments of Pathology at the Children's Hospital, and Department of Pediatrics at University or Cincinnati Medical Center, Cincinnati, Ohio

Abstract

It has been argued that fetal and placental infections decrease the incidence of hyaline membrane disease (HMD). However, others contend that this is not so. We performed a rigidly controlled clinicopathologic investigation of one group of infants with evidence of severe antenatal infection compared with another group free of infection. This study shows that placental infection correlates positively with neonatal sepsis and that in this series of patients neither infection nor prolonged rupture of membranes is associated with a decrease of HMD. Our data do not support the proposal that antenatal infections protect the neonate against later development of HMD.