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Obstetrics & Gynecology 1975;46:511-516
© 1975 by The American College of Obstetricians and Gynecologists
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Histogenesis of Leiomyomatosis Peritonealis Disseminata (Disseminated Fibrosing Deciduosis)

TIM H. PARMLEY, MD. FACOG, J DONALD WOODRUFF, MD. FACOG, KEVIN WINN, MD, J W C JOHNSON, MD, FACOG and PAUL H. DOUGLAS, MD

From the Departments of Obstetrics and Gynecology and Pathology. The Johns Hopkins University School of Medicine. Baltimore. Maryland and the Department of Obstetrics and Gynecology. The York Hospital. York. Pennsylvania

Abstract

Leiomyomatosis peritonealis disseminata (LPD) is a rare clinical entity. Widespread subperitoneal nodules of apparent smooth muscle arc found in patients who are pregnant or have recently been so. This clinical appearance together with mitotic figures found in frozen sections suggests malignancy. We believe, in contrast, that LPD is a benign reparative process in which fibroblasts replace subperitoneal decidua.






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Copyright © 1975 by the American College of Obstetricians and Gynecologists.