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Obstetrics & Gynecology 1975;46:489-499
© 1975 by The American College of Obstetricians and Gynecologists
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THE APPLICATIONS OF STEROID HORMONE RADIOIMMUNOASSAYS TO CLINICAL OBSTETRICS

JOHN E. BUSTER, MD and GUY E. ABRAHAM, MD

From the Department of Obstetrics and Gynecology, William Beaumont Army Medical Center, El Paso, Texas and the Division of Reproductive Biology, Department of Obstetrics and Gynecology, UCLA School of Medicine, Harbor General Hospital, Torrance, California.

This is a selective survey of recent publications dealing with theoretical and established applications of steroid hormone radioimmunoassay procedures applied to clinical obstetric investigation. This subject is reviewed in three sections: first, basic principles of steroid hormone radioimmunoassay methodology; second, steroidogenesis in normal pregnancy and its relation to patterns of steroid hormones measured in maternal and fetal circulations; third, applied steroid radioimmunoassay technology as it is being used in established and potential clinical applications. It is concluded that steroid hormone radioimmunoassay procedures have been and will continue to be a highly productive technology applied to clinical obstetric investigation.




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