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Obstetrics & Gynecology 1975;46:360-361
© 1975 by The American College of Obstetricians and Gynecologists
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INTRAEPITHELIAL VAGINAL NEOPLASIA FOLLOWING IMMUNOSUPPRESSIVE THERAPY TREATED WITH TOPICAL 5-FU

P. BOWEN-SIMPKINS, MA, MB BCHIR, MRCOG and M. G. R. HULL, MB BS, MRCOG

From the Department of Obstetrics and Gynaecology, St. Mary's Hospital Medical School, London, England.

Abstract

A case is reported of the successful treatment of multifocal intraepithelial neoplasia of the vagina by topical application of a cytotoxic agent, 5-fluorouracil. These lesions followed prolonged immunosuppressive therapy after renal transplantation. Intraepithelial neoplasia Has present also in the cervix and was treated by conization.






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