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Renal Scleroderma and Pregnancy

From the Department of Obstetrics and Gynecology, Akron General Medical Center, Akron, Ohio 44307

Abstract

A case of renal scleroderma resulting in maternal death is reported. The literature reveals that scleroderma is commonly worsened by, and often adversely affects, pregnancy. Renal scleroderma in pregnancy, however, has been reported only twice before. Both were cases of maternal mortality in which the series of events leading to death were strikingly similar to the circumstances in the present case. The pregnancy in all 3 cases was uneventful until the third trimester, when preeclampsia suddenly developed, renal failure rapidly ensued, and death followed within days. So grave is the prognosis for mother and fetus in sclerodermal renal disease, that it seems reasonable to recommend the immediate termination of a pregnancy associated with scleroderma when the first sign of preeclampsia with any evidence of diminishing renal function occurs.

This article has been cited by other articles:

				V. D. STEEN Pregnancy in Women With Systemic Sclerosis Obstet. Gynecol., July 1, 1999; 94(1): 15 - 20. [Abstract] [Full Text] [PDF]