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Obstetrics & Gynecology 1974;44:215-218
© 1974 by The American College of Obstetricians and Gynecologists
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Diagnosis of Fetal Death In Utero by Elevated Amniotic Fluid CPK Levels

T. KERENYI, MD, FACOG and L. SARKOZI, PhD

From the Department of Obstetrics and Gynecology and Department of Chemistry, The Mount Sinai Hospital and The Mount Sinai School of Medicine of The City University of New York.

Abstract

Elevated amniotic fluid creatine phosphokinase (CPK) levels were found in all tested cases of fetal death in utero. The CPK appears to be fetal in origin and accumulates in the amniotic fluid, presumably as a result of fetal tissue decomposition. Creatine phosphokinase concentrations seem also to reflect the time interval elapsed following fetal demise.






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Copyright © 1974 by the American College of Obstetricians and Gynecologists.