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Obstetrics & Gynecology 1974;44:77-83
© 1974 by The American College of Obstetricians and Gynecologists
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Carcinoma of the Cervix

Clinical Experience During a 10-Year Period 1958–1967

MOSTAFA A. SELIM, MD, FACOG, JULIET L. SO-BOSITA, MD, A. BRIAN LITTLE, MD, FACOG and W. TOPOLNICKI, MD

From the Department of Reproductive Biology, Case Western Reserve University, and the Departments of Obstetrics and Gynecology and Radiotherapy. Cleveland Metropolitan General Hospital, Cleveland, Ohio.

A total of 198 patients with carcinoma of the cervix of all stages were studied. Twenty received no treatment; others were treated with surgery, irradiation, or both. Data on staging, modes of treatment, and survival rates are reported. Patients with a few pregnancies had a higher incidence of Stages I and II {early) cancer and a good prognosis, whereas nulligravidas or multigravidas had a higher incidence of Stage III and IV (advanced) cancer and a poor prognosis. The results indicated that clinical stage was the most important prognostic factor in cancer of the cervix, but the patient's gravidity and the histologic grade of the cancer also need to be considered. Radical surgery in the series reported here could not be evaluated adequately, as it was used mostly in patients with Stage IA (microinvasive) cancer, and the number of cases was very small. From our results, standardization of therapy for all stages of cancer of the cervix docs not appear to be the optimal method of therapy. According to the accumulated extensive experience reported in the literature, advanced lesions need higher doses of external irradiation than lesions in the early stages if the rate of survival is to be improved.






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Copyright © 1974 by the American College of Obstetricians and Gynecologists.