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Obstetrics & Gynecology 1974;43:872-877
© 1974 by The American College of Obstetricians and Gynecologists
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Use of Ultrasound for Placental Localization in Genetic Amniocentesis

M. MISKIN, MD, T. A. DORAN, MD, N. RUDD, MD, H. A. GARDNER, MD, S. LIEDGREN, MD and R. BENZIE, MD

Departments of Radiology, Obstetrics and Gynecology, Genetics, and Pathology, at the University of Toronto, Toronto, Ontario, Canada.

The use of diagnostic ultrasound to localize the placenta prior to genetic amniocentesis has resulted in a 10-fold reduction in bloody taps. Ultrasound has had no adverse effects on the growth of amniotic cells in tissue culture nor has damage to chromosomes been demonstrated. Insonation of fetuses in intact amniotic sacs removed at hysterotomy has similarly shown no interference with in vitro growth potential and no chromosomal damage to cells derived from amniotic fluid, fetal skin, or fetal thymus.






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