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Intrauterine Infection on an Obstetric Service

Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut.

One hundred twenty-three patients were studied prospectively for amnionitis and endometritis. Amniotic fluid was obtained for microscopic examination and culture from 62 patients. Sixteen of these patients were found to have one or more polymorphonudear leukocytes (PMN)/HPF of amniotic fluid, and all of these patients developed clinical amnionitis and/or endometritis. Bacteria were present on culture whenever PMN's were noted; however, the infection rate was not increased if bacteria were found without PMN's. Eighty-six patients had internal fetal monitoring during labor. Those patients who became infected and had ruptured membranes during 8 or more hours of labor had significantly longer internal monitor applications than uninfected patients.