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Hypervitaminosis A and Congenital Renal Anomalies in a Human Infant

From the Departments of Pediatrics, Kaiser-Permanente Medical Center Santa Clara, and Stanford University Medical Center, Stanford, California.
Send reprint requests to Irwin B. Bernhardt, MD Department of Pediatrics The Permanente Medical Group 900 Kiely Blvd Santa Clara, CA 95051

Hypervitaminosis A during organogenesis has been shown in animals to be teratogenic. A similar relation in man is suggested by the birth of a child, with congenital renal anomalies resulting in obstructive salt-losing nephropathy, to a mother who had taken excessive amounts of vitamin. A throughout pregnancy.

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