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Obstetrics & Gynecology 1974;43:571-572
© 1974 by The American College of Obstetricians and Gynecologists
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Some Thoughts on Assessing the Effectiveness of Passive Immunization to Rh

J SUSAN JOHNSON, MD and EVERETT M. CLAYTON, JR, MD

From the Department of Obstetrics and Gynecology, Vanderbilt University Hospital, Nashville, Tennessee

Abstract

Experience has shown that there is a rare sensitization to the Rh during pregnancy and an occasional failure to protect against sensitization in the postpartum period. These cannot always be related to the amount of antigen present. But if all postabortal and postpartum patients at risk receive anti-D immune globulin and are carefully screened for large fetomaternal bleeds by the use of direct counting of fetal red cells in the maternal circulation, the number of failures to protect against Rh sensitization can be reduced to an undiminishable minimum.






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Copyright © 1974 by the American College of Obstetricians and Gynecologists.