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Critical Analysis of the Amniotic Fluid Shake Test

From the Department of Obstetrics and Gynecology of the University of Miami School of Medicine, Miami, Florida

Abstract

Multiple studies were performed on 121 amniotic fluid samples obtained from 119 women. The fluid was analyzed for its Iecithin-sphingomyclin (L/S) ratio, foam stability, bilirubin (ODco,), creatinine, and amniotic fluid/blood creatinine ratio. In addition, comparisons were made with the neonatal outcome. It was found that in comparison to the L/S ratio, the foam or shake test had a false-positive rate of 18% and a false-negative rale of 7%. This was found to be as sensitive and specific or better than the other fluid parameters. Of 7 infants who developed respiratory distress syndrome (RDS), 5 were predicted by both the foam test and L/S ratio and, although 2 had mature amniotic fluids, complicated deliveries probablv contributed to a transient mild RDS.

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