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Obstetrics & Gynecology 1974;43:41-45
© 1974 by The American College of Obstetricians and Gynecologists
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Blood Disappearance Rates of Certain Hormones and Enzymes Advocated as Fetoplacental Function Tests

C DEANS CRYSTLE, MD, FRANK BREUNING, MD, NORMAN H. DUBIN, PhD, GEORGE F. GRANNIS, PhD, VERNON C. STEVENS, PhD and JOHN D. TOWNSLEY, PhD

From the Pregnancy Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda. Maryland anil the Departments of Obstetrics and Gynecology and Pathology. Ohio State University, Columbus. Ohio and the Department of Obstetrics and Gynecology, University of Maryland. Baltimore, Maryland

Abstract

The puerperal blood disappearance rates of three hormones (unconjugated 17ß estradiol, total estriol, and human chorionic somatomammotropin) and three enzymes (heat stable alkaline phosphatase, cystine aminopeptidase, and diamine oxidase) purported to be useful as indices of fetoplacental status have been simultaneously determined in 7 subjects. Disappearance rates of the hormones were faster (minutes) than the enzymes (days) providing a theoretic lime advantage of the former in minimizing time lost between fetoplacental compromise and its earliest possible detection.






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Copyright © 1974 by the American College of Obstetricians and Gynecologists.