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From the Department of Obstetrics and Gynecology at The Memorial Hospital, Worcester, Massachusetts
In 33 infants, amniotic fluid and gastric aspirate were tested for pulmonary surfactant by the "Foam lest." In 25 of 29 mature infants (82%), the two substrates correlated with positive liters (1:2, or 1:4). Four cases did not correlate; in these the gastric substrate was acid. There is a 100% correlation when only cases with alkaline gastric substrates are considered. In 3 of 4 premature infants, the specimens tested similarly with low liters (1:1, or 1:1.3); all had respiratory distress. The 1 which did not correlate had acid gastric content. Gastric aspirate will respond to the "Foam test" if it is alkaline and can he used to determine pulmonary surfactant.
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