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Cryosurgical Treatment of Cervical Intraepithelial Neoplasia

From the Department of Obstetrics and Gynecology, Baylor College of Medicine. Houston. Texas and Harris County Hospital District. Houston. Texas.

There have been 190 women with intraepithelial neoplasia of the cervix, varying from mild-moderate dysplasia to squamous cell carcinoma in situ, treated with cryosurgery. Follow-up study revealed no evidence of residual atypia in 170 of these women. Of the 20 with residual atypia in the cervix, 7 were found to have carcinoma in situ. In 6 of these, the epithelial atypia was high in the endocervical canal. Currently, women with evidence of atypical epithelium in the endocervical scrapings, or who have colposcopic evidence of disease beyond the line of vision, have diagnostic and therapeutic conization performed rather than treatment with cryosurgery.

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