Obstetrics & Gynecology Email Alerts
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Obstetrics & Gynecology 1973;42:644-650
© 1973 by The American College of Obstetricians and Gynecologists
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by DISAIA, P. J.
Right arrow Articles by TOWNSEND, D. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by DISAIA, P. J.
Right arrow Articles by TOWNSEND, D. E.

Antibody Cytotoxicity Studies in Ovarian and Cervical Malignancies

PHILIP J. DISAIA, MD, RICHARD H. NALICK, MD and DUANE E. TOWNSEND, MD, FACOG

Departments of Obstetrics and Gynecology and Radiology at Los Angeles County-University of Southern California Medical Center. Los Angeles, California.

This study evaluates the cytotoxic affect of serum from patients with progressive squamous cell carcinoma of the cervix and adenocarcinoma of the ovary prior to treatment. The cytotoxic ability of six specific rabbit antisera prepared by immunizing rabbits with fresh tissue homogenates of adenocarcinoma of the ovary were also studied and all six demonstrated a definite injurious affect. Twelve of the 20 patients with advanced squamous cell carcinoma of the cervix and 5 of the 8 patients with advanced adenocarcinoma of the ovary also illustrated a definite cytocidal serum activity. Explanations for the concomitant presence of cytotoxic antibodies and progressive disease are suggested.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American College of Obstetricians and Gynecologists.