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The Influence of Epidural Anesthesia on Uterine Blood Flow

From the Department of Obstetrics and Gynecology at State University of New York, Down-state Medical Center, Brooklyn, NY and the Department of Anesthesiology at the Coney Island Hospital affiliated with the Maimonides Medical Center, Brooklyn, New York.

Epidural anesthesia in labor administered as repeated doses of 4–5 ml Carbocaine either did not cause any change in uterine blood flow (UBF) baseline or was attended by an increase in UBF. No change in periodic UBF undulations during the uterine contraction cycle was evident. A larger dose of Carbocaine (7 ml) produced a temporary decline in UBF coinciding with systemic hypotension. The fact that the decrease in UBF did not occur without simultaneous hypotension supports the view that the decline in UBF is mediated through the change in blood pressure.