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Obstetrics & Gynecology 1973;42:172-181
© 1973 by The American College of Obstetricians and Gynecologists
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Transient Luteolytic Effect of Prostaglandin F2{alpha} in the Human

ANNE COLSTON WENTZ, MD and GEORGEANNA SEEGAR JONES, MD

From the Department of Gynecology and Obstetrics at The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Prostaglandin F2{alpha} was infused into 13 nonpregnant volunteers at a rate of 50 µg/minute for 8 hours. Ten subjects had a shortened Iuteal phase. Nine subjects had decreased progesterone values at 8 hours, ranging from 23.5 to 69.8% of baseline values. No consistent changes in plasma estradiol or estrone were noted. The significance of these findings is discussed.




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R. L. Bogan, M. J. Murphy, R. L. Stouffer, and J. D. Hennebold
Prostaglandin Synthesis, Metabolism, and Signaling Potential in the Rhesus Macaque Corpus Luteum throughout the Luteal Phase of the Menstrual Cycle
Endocrinology, November 1, 2008; 149(11): 5861 - 5871.
[Abstract] [Full Text] [PDF]


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