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Obstetrics & Gynecology 1973;41:920-924
© 1973 by The American College of Obstetricians and Gynecologists
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Discordance of Vaginal Agenesis in Monozygotic Twins

JON H. LISCHKE, MD, CLIFFORD H. CURTIS, MD, FACOG and EMMET J. LAMB, MD, FACOG

From the Department of Gynccology and Obstetrics at Stanford University School of Medicine, Stanford. California

Abstract

Three patients with vaginal agenesis are reported. Each has a normal monozygotic twin. The embryology of the Mullerian system and the familial occurrence of vaginal agenesis and vaginal septa arc reviewed. Vaginal agenesis associated with other congenital defects in siblings, as reported by others, is probably caiued by an autosomal recessive gene. Discordance of vaginal agenesis in identical twins, as reported here, makes an exclusively genetic etiology unlikely




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P. Oppelt, P.L. Strissel, A. Kellermann, S. Seeber, A. Humeny, M.W. Beckmann, and R. Strick
DNA sequence variations of the entire anti-Mullerian hormone (AMH) gene promoter and AMH protein expression in patients with the Mayer-Rokitanski-Kuster-Hauser syndrome
Hum. Reprod., January 1, 2005; 20(1): 149 - 157.
[Abstract] [Full Text] [PDF]


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Copyright © 1973 by the American College of Obstetricians and Gynecologists.