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Obstetrics & Gynecology 1973;41:833-836
© 1973 by The American College of Obstetricians and Gynecologists
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Pulmonary Surfactant

Is the Fetal Adrenal Necessary?

RONALD K. BURKE, MD, LAURENCE E. LUNDY, MD, FACOG, THOMAS R. SISSON, MD and FAGIR M. JAHED, MD

From the Departments of Obstetrics and Gynecology and Pediatrics, Temple University Medical School, Philadelphia, Pennsylvania

Abstract

The amniotic fluid lecithin-sphingomyelin ratio was studied in a patient who delivered an anencephalic fetus. The ratio was 3:1 at the thirty.nfth week of gestation. Study of the anencephalic infant at 1 and 4 days of age showed minimal adrenal cortical function. We conclude that normal fetal adrenal cortical function is not required for the production of pulmonary surfactant






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Copyright © 1973 by the American College of Obstetricians and Gynecologists.