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Obstetrics & Gynecology 1973;41:579-584
© 1973 by The American College of Obstetricians and Gynecologists
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Management of Autoimmune Thrombocytopenia in Pregnancy and in the Neonate

MARY TERRITO, MD, JERRY FINKLESTEIN, MD, WILLIAM OH, MD, CALVIN HOBEL, MD and HERMAN KATTLOVE, MD

From the Departments of Medicine, Pediatrics and Gynecology and Obstetrics, University of California at Los Angeles, Harbor General Hospital. Turrance, California

Abstract

Five new case reports of autoimmune thrombocytopenic purpura during pregnancy are presented and 80 previously reported cases are reviewed. Children born to mothers who had platelet counts of less than 100,000/cu mm at delivery (Group I) had a 799% incidence of thrombocytopenia, whereas children born to mothers with pi at let counts greater than 100,000/cu mm (Group II) had only a 27% incidence of thrombocytopenia. Risks of labor and delivery to the thrombocytopenia baby and mother are discussed. It is suggested that Group I mothers be delivered by cesarean section, and Group II mothers be delivered vaginally, except when operative forceps are contemplated in which case cesarean section should he used instead. Treatment of the thrombocytopenia newborn with platelet transfusions, exchange transfusions, steroids or observation alone is discussed.




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K. E. Webert, R. Mittal, C. Sigouin, N. M. Heddle, and J. G. Kelton
A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura
Blood, December 15, 2003; 102(13): 4306 - 4311.
[Abstract] [Full Text] [PDF]


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