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Obstetrics & Gynecology 1973;41:501-506
© 1973 by The American College of Obstetricians and Gynecologists
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Efficacy of Cryosurgical Treatment of Severe Cervical Intraepithelial Neoplasia

WILLIAM T. CREASMAN, MD, FACOG, JOHN C. WEED, JR, MD, STEPHEN L. CURRY, MD, WILLIAM W. JOHNSTON, MD and ROY T. PARKER, MD, FACOG

From the Department of Obstetrics and Gynecology. Division of Oncology, and the Department of Pathology at Duke University Medical Center, Durham, North Carolina

Abstract

In an attempt to identify a satisfactory method of office management of young women with severe intraepithelial neoplasia, cryosurgery was evaluated. Seventy-five patients in whom cytology and biopsy demonstrated severe dysplasia or carcinoma in situ had cryosurgery treatment of the cervix before planned conization or hysterectomy. Of the 27 patients receiving a single freeze, 48.5% had severe dysplasia or a more advanced lesion remaining in the operative specimen. Of 48 patients undergoing the "double freeze" technic, only 18.7% had severe dysplasia or carcinoma in situ in the surgical specimen. In the young, low-parity patients, only 3 of 24 (12.5%) had severe dysplasia or carcinoma in situ after freezing. Cryosurgery can eradicate severe cervical intraepithelial neoplasias and may be used as an alternative to conization or hysterectomy in the selected group of young, low-parity patients.




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C. H. HOLSCHNEIDER, K. GHOSH, and F. J. MONTZ
See-and-Treat in the Management of High-Grade Squamous Intraepithelial Lesions of the Cervix: A Resource Utilization Analysis
Obstet. Gynecol., September 1, 1999; 94(3): 377 - 385.
[Abstract] [Full Text] [PDF]


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