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Estriol and Creatinine in Pregnancy Urine

From the Rees-Stcaly Clinic Research Foundation, San Diego, Calif

Abstract

Estriol and crcatinine in urine of 5 women were determined at frequent intervals during the last trimester. The overall trend was similar when excretion of estriol was expressed in terms of milligrams per 24 hours and milligrams per gram of creatinine excreted during the same period. However, there was less day-to-day variability in the excretion of estriol when expressed relative to the concentration of creatinine. This study concludes that crcatininc provides a useful indicator of the completeness of a 24-hour collection of urine when using changes in excretion of estriol to monitor for potential fetal distress.