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Obstetrics & Gynecology 1972;40:681-685
© 1972 by The American College of Obstetricians and Gynecologists
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Malignant Hypertension, Uremia and Hemolytic Anemia in a Patient on Oral Contraceptives

HECTOR TOBON, MD

From the Department of Pathology, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pittsburgh, Pa 15213.

Abstract

A 44-year-old gravida 3, para 3, whose last child had been delivered 19 months previously and who had been taking norethindrone acetate and ethynyl+estradiol tablets, 2 mg, for approximately 1 1/2 years developed malignant hypertension, uremia and microangiopathic hemolytic anemia. Autopsy revealed the stigmata of malignant hypertension with widespread arteriolar necrosis, fragmentation of the arteriolar wall and thrombosis with recent infarcts in the kidneys and pancreas. It is suggested that the blood pressure of patients on oral contraceptives be evaluated periodically.






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Copyright © 1972 by the American College of Obstetricians and Gynecologists.