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Obstetrics & Gynecology 1972;40:607-611
© 1972 by The American College of Obstetricians and Gynecologists
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Discordant Anencephaly in a Set of Triplets

H. G. KOHLER, MD and H. N. MACDONALD, MD

From The Maternity Hospital at Leeds, Hyde Terrace, Leeds, 2, England.

Abstract

A triplet pregnancy of a woman who had previously had an anencephalic stillbirth resulted in delivery of 2 normal infants (I and III) and I anencephalic monster (II) who had a separate amnion but shared a chorionic sac with her sister I. Triplet III had a separate chorion. Blood group studies added supportive evidence for the monozygosity of I and II. At autopsy it was found that the adrenal glands of triplet II, though small, were not as severely hypoplastic as those of most anencephalics; moreover, there was an appreciable fetal zone. It is suggested that this may have been caused by hormonal stimulation received from the normal synchorionic cotriplet.






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