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Obstetrics & Gynecology 1972;40:366-370
© 1972 by The American College of Obstetricians and Gynecologists
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Prevention of Rh Immunization After Abortion with Anti-Rho (D)-Immunoglobulin

JACK A. GOLDMAN, MD and BENJAMIN ECKERLING, MD

From the Department of Obstetrics and Gynaecology, Beilinson Medical Center, Tel-Aviv University Medical School, Tel-Aviv, Israel.

Abstract

Rh antibody levels were titrated in 170 Rhnegative women who underwent abortion during a period of 6 months or more. Anti-Rho (D) immunoglobulin, in a dose of 200 µg completely prevented the appearance of Rh antibody after spontaneous and artificial abortion in 48 women, whereas 5 of 122 untreated controls were immunized. These results parallel the excellent results obtained with such therapy postpartum. Anti-Rho (D) immunoglobulin should be administered after abortion to every Rh-negative woman who has not already been immunized to the Rh factor.






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Copyright © 1972 by the American College of Obstetricians and Gynecologists.