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Amenorrhea and Galactorrhea

From the Endocrine Clinic, Chelsea Hospital for Women.

Abstract

Thirteen patients with symptoms of secondary amenorrhea and galactorrhea and 1 with galactorrhea alone have been studied. These symptoms developed in 5 after they discontinued taking oral contraceptives, in 4 after delivery; no apparent cause for the symptoms could be found in 2 patients, a pituitary tumor was diagnosed in 1, cystic mastitis in 1 and in 1 the features developed during treatment with phenothiazines. The possibility that patients could become pregnant either spontaneously or after treatment with clomiphene or pituitary gonadotrophin was most favorable in those who developed their symptoms postpartum. Specific efforts should be made to exclude a pituitary tumor as a cause of the symptoms.