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From the Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27514.
Abstract
Investigations using PGF2a, for therapeutic abortion are currently in progress in several centers. This case report describes an asthmatic attack during intravenous administration of PGF2a, to a patient with a history of bronchial asthma. Moderately severe bronchoconstriction was noted clinically during infusion of 200 µg/min. The symptoms cleared rapidly soon after the drug was discontinued. The literature on respiratory effects of prostaglandins is reviewed.
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