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Clinical Research, Veneral Disease Branch, State and Community Services Division, Center for Disease Control, Atlanta, Ga 30333.
Abstract
Controlling the gonorrhea epidemic in the United States will depend on good clinical management of individual infected patients. The diagnoses of Neisseria gonorrhoeae infections can best be made with culture using Thayer-Martin selective medium or a new transport medium, Transgrow, if optimal technics for obtaining and handling culture specimens are used. The reason for therapy failure in many cases is not the development of partially resistant gonococcal isolates, but the use of ineffective antibiotics as well as inadequate dosage. A survey of recent studies documents that adequate doses of procaine penicillin with probenecid or tetracycline remain effective therapy for acute N gonorrhoeae infection.
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