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Obstetrics & Gynecology 1972;39:218-224
© 1972 by The American College of Obstetricians and Gynecologists
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Use of a Prophylactic Antibiotic in Elective Major Gynologic Operations

JAMES L. ALLEN, MD, JOHN F. RAMPONE, MD and CLIFFORD R. WHEELESS, MD

Department of Gynecology and Obstetrics, The Johns Hopkins University and The Johns Hopkins Hospital, Baltimore, Md 21205.

Abstract

The use of a prophylactic antibiotic in elective gynologic operations was evaluated in a prospective, double-blind, controlled study. Morbidity in those patients undergoing abdominal hysterectomy was 41% in the placebo group, and 14.1% in the drug group. In patients undergoing vaginal hysterectomy morbidity was 50% in the control group and 4.1% in the drug group. More experienced surgeons had the same rate of morbidity as inexperienced ones. Hospital stay was significantly reduced for abdominal and vaginal hysterectomy patients treated with the drug.






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Copyright © 1972 by the American College of Obstetricians and Gynecologists.