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Melanoma of the Vulva

From the Sections of Obstetrics and Gynecology and Gynecologic Surgery, and the Graduate School of Medicine, the Mayo Clinic and Mayo Foundation, Rochester, Minn.

Abstract

In 29 patients with melanoma of the vulva, treated from 1950 through 1968, the lesions varied in size from a few millimeters to 6.0 cm and tended to be located near the midline, with the clitoris and periclitoral areas being involved in 11 of 29 tumors and the labia majora in only 6. Lymph nodes were metastatically involved in 7 of the 29 patients; in 2 of these, both superficial and deep nodes were involved. Of 21 patients eligible for 5-year follow-up study, 7 (33%) lived 5 or more years. There was one operative death in this series. Adequate surgical treatment consists of single-state en bloc dissection of the inguinal, femoral, and deep pelvic nodes and radical vulvectomy. This should be extended to include vaginectomy or anterior, posterior, or total exenteration, if indicated by the size or location of the tumor.

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