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Obstetrics & Gynecology 1970;35:364-370
© 1970 by The American College of Obstetricians and Gynecologists
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Drug-Induced Hydrops in the Fetal Lamb

EDGAR O. HORGER, III, MD and DONALD L. HUTCHINSON, MD, FACOG

From the Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pittsburgh, Pa.

Abstract

In an effort to produce an experimental biologic model simulating human erythroblastosis and hydrops fetalis, fetal lambs were exsanguinated slowly or were treated with a hemolytic agent. Although fetal anemia did result, no hydrops was observed. When a protein inhibitor was added to the treatment, hydropic changes were produced more consistently even though there was no measurable decrease in the fetal plasma protein concentration.




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G. P. Giacoia
Hydrops Fetalis (Fetal Edema): A Survey
Clinical Pediatrics, May 1, 1980; 19(5): 334 - 339.
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