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Rubella Antibody Screening in a Prenatal Clinic Using the Indirect Fluorescent Method

WATSON A. BOWES, Jr, MAJ, MC^*, JACK L. GIBSON, COL, MC, FACOG^*, ALBERT LEIBOVITZ, COL, MSC and WILLIAM J. PALIN, SP5

*OB-GYN Service, Madigan General Hospital, Tacoma, Wash.
Department of Microbiology, Sixth US Army Medical Laboratory, Fort Baker, Calif.

Abstract

For 1734 prenatal patients the indirect immunofluorescent antibody method was used to determine the presence of rubella antibody: 17% were found to have antibody titers less than 1:8 pointing to their susceptibility to rubella infection. There was a significantly greater frequency of seronegative patients among Orientals and among those who had no history of rubella infection. Patients tested for rubella antibody are provided documentation of their immunity for future reference. Rubella antibody screening during pregnancy identifies a group of seronegative women who are ideal candidates for postpartum rubella immunization.