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Obstetrics & Gynecology 1969;34:874-880
© 1969 by The American College of Obstetricians and Gynecologists
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Antepartum Thrombophlebitis

Morbidity with Long-Term Heparin and a Proposed Regimen of Therapy

MAURICE J. MUELLER, Jr, LCDR, USN (MC)* and THOMAS B. LEBHERZ, CAPT, USN (MC), (RET), FACOG{dagger}

*Present address: Naval Hospital, Charleston, SC 29408
{dagger}From the Department of Obstetrics and Gynecology, Naval Hospital, San Diego, Calif. Present address: Cleveland Metropolitan Hospital, Cleveland, Ohio 44109

Ten gravidas with antepartum deep-vein thrombophlebitis were observed and treated during a 3-year period. Seven of the 10 mothers suffered hemorrhagic complications while being given long-term treatment with heparin. A regimen of varying periods of heparin usage is proposed, depending on the patient's prior history. Such treatment is discontinued during labor and resumed post partum, together with CoumadinR.






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