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Tissue Activator of the Fibrinolytic Enzyme in the Female Reproductive System

GERSON WEISS, MD^* and FRITZ K. BELLER, MD, FACOG

*From the Department of Obstetrics and Gynecology, NIH Research Trainee for Reproductive Physiology, New York University School of Medicine, New York
From the Department of Obstetrics and Gynecology, Career Scientist of the Health Research Council of the City of New York (I 297), New York University School of Medicine, New York

Abstract

Tissue from the female genital tract was systematically examined for activator activity of the fibrinolytic enzyme system using the autographic technic of Todd. Endothelium-lined channels were highly active. Much activator was found in musculature of both corpus uteri and fallopian tube, as well as in the racemose glands of the endocervical lining. Comparatively little activity was found in the endometrium. It is irregularly present in proliferative endometrium but diffusely distributed in secretory endometrium. Stratified squamous epithelium and submucosal fibrous tissue found to be inactive.