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Chromosome Constitution of Endometrium

From the Department of Obstetrics and Gynecology, Sinai Hospital of Detroit, Detroit, Mich, and The Hartford Cytogenetic Laboratory, Washington University School of Medicine, St. Louis, Mo.

Abstract

Study of the chromosomal content of endometrial cells by means of three methods—direct squash, tissue culture squash, and air-dried cell suspension—showed consistent pattern of 46XX. Aneuploidy was associated with broken cells; it was not characteristic of endometrial cells associated with amenorrhea, habitual abortion, infertility of unknown origin, or abnormal hormonal state. Caution is urged in interpretation of aneuploidy, especially from squash preparations.