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Obstetrics & Gynecology 1969;34:249-251
© 1969 by The American College of Obstetricians and Gynecologists
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Effect of Selected Estrogens and Progestins on Human Chromosomes In Vitro

MORTON A. STENCHEVER, MD, FACOG, JANE A. JARVIS, MT and N KRISTINE KREGER, BA

From the Department of Reproductive Biology, Case Western Reserve University, School of Medicine, Cleveland, Ohio

Abstract

Several of the estrogens and progestins constituting the widely used contraceptive pills were added individually in varied concentrations to cultures of lymphocytes grown from the blood of healthy women. When compared to control cultures and evaluated in blind fashion, the in-vitro studies uncovered no obvious chromosomal effects.




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