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Obstetrics & Gynecology 2007;109:547-549
© 2007 by The American College of Obstetricians and Gynecologists
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CASE REPORTS

Ovarian Hyperstimulation Syndrome Caused by Pituitary Gonadotroph Adenoma Secreting Follicle-Stimulating Hormone

Mohammadreza Ghayuri, MD1 and James H. Liu, MD1

From the 1Department of Obstetrics and Gynecology, MacDonald Women’s Hospital, Case Western Reserve University, Cleveland, Ohio.

BACKGROUND: We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels.

CASE: A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regular menstrual cycles and subsequently conceived.

CONCLUSION: Ovarian hyperstimulation caused by a gonadotroph adenoma in a premenopausal woman with normal FSH levels is extremely rare. However, we propose that gonadotroph adenomas be considered in the differential diagnosis of patients who have this constellation of abnormalities.




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T. Kajitani, S. Liu, T. Maruyama, H. Uchida, R. Sakurai, H. Masuda, T. Nagashima, M. Ono, T. Arase, and Y. Yoshimura
Analysis of serum FSH bioactivity in a patient with an FSH-secreting pituitary microadenoma and multicystic ovaries: A case report
Hum. Reprod., February 1, 2008; 23(2): 435 - 439.
[Abstract] [Full Text] [PDF]


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