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Induction of Labor Using a Foley Balloon, With and Without Extra-Amniotic Saline Infusion

From the Department of Obstetrics and Gynecology, Virginia Commonwealth University Medical Center, Richmond, Virginia.

OBJECTIVE: To compare transcervical Foley bulb with and without extra-amniotic saline infusion for induction of labor in patients with an unfavorable cervix.

METHODS: Women who presented for induction of labor with Bishop score less than 5 were randomly assigned to receive Foley alone or Foley with extra-amniotic saline infusion for induction of labor. Primary outcome was time from start of induction to vaginal delivery. Secondary outcomes were cesarean delivery rates, incidence of chorioamnionitis, Apgar scores at 1 and 5 minutes, and adverse events.

RESULTS: One hundred forty women completed the study. Time from induction to vaginal delivery was 16.58 (± 7.55) hours in the extra-amniotic saline infusion group compared with 21.47 (± 9.95) hours in the Foley group (P < .01). Chorioamnionitis occurred in 4 of 66 (6.1%) women in the extra-amniotic saline infusion group compared with 12 of 74 (16.2%) women in the Foley group (P = .067). Cesarean delivery rate was 21.2% versus 20.1% in the extra-amniotic saline infusion and Foley groups, respectively (P = 1.0). Median 1-minute and 5-minute Apgar scores were 9 in both groups. Adverse events were rare and unrelated to method of induction.

CONCLUSION: Induction of labor by using Foley with extra-amniotic saline infusion results in shorter induction-to-vaginal-delivery time than Foley alone, without affecting cesarean delivery rates.

LEVEL OF EVIDENCE: II-1

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				M. G. Lin, K. J. Reid, M. R. Treaster, F. S. Nuthalapaty, P. S. Ramsey, and G. C. Lu Transcervical Foley Catheter With and Without Extraamniotic Saline Infusion for Labor Induction: A Randomized Controlled Trial Obstet. Gynecol., September 1, 2007; 110(3): 558 - 565. [Abstract] [Full Text] [PDF]