HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Myers, E. R. Search for Related Content PubMed PubMed Citation Articles by Myers, E. R. Related Collections Immunology

Prospective Data Collection of a New Procedure by a Specialty Society

The FIBROID Registry

From the Department of Obstetrics and Gynecology, Duke Clinical Research Institute, and Department of Medicine, Duke University Medical Center, Durham, North Carolina; Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California; Society for Interventional Radiology Foundation, Fairfax, Virginia; Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Department of Public Health Sciences, University of Toronto, Ontario, Canada; Department of Radiology, Georgetown University Medical Center, Washington, DC; and Image Guided Surgery Associates, Philadelphia, Pennsylvania.

Objective: To describe registry methods and baseline patient demographics from a national sample of women undergoing uterine artery embolization for uterine leiomyomata.

Methods: Interventional radiology practices were recruited to submit data by a secure Web site on women undergoing uterine artery embolization for symptomatic leiomyomata. Baseline data included patient demographics, prior medical, surgical, and obstetrical history, uterine anatomy, and quality-of-life measures. Subsequent data collected included details of the uterine artery embolization procedure and hospital stay and outcomes at 30 days; patients were also offered the opportunity to participate in longer-term follow-up. Characteristics of white and African-American women were compared using t tests, ², or Wilcoxon rank-sum tests as appropriate.

Results: As of December 31, 2002, 3,319 uterine artery embolization cases had been entered into the registry by 72 sites; number of patients entered by individual sites ranged from 1 to 514. Of these patients, 95.4% consented to participation in the short-term outcomes registry. Forty-eight percent of patients were African American, and 44.4% were white and non-Hispanic. Heavy menstrual bleeding was the single most bothersome symptom in 64.3% of patients. Compared with white non-Hispanic women, African-American women were significantly younger, more likely to be obese, had larger uteri and more numerous leiomyomata, more severe symptoms, and poorer quality-of-life scores before treatment.

Conclusion: It is feasible to collect prospective data on new technologies. The FIBROID Registry prospectively collected data on more than 3,000 women undergoing uterine artery embolization for symptomatic leiomyomata. Baseline patient characteristics of this patient population seem to be similar to those of women undergoing other procedures for leiomyomata.

Level of Evidence: III

This article has been cited by other articles:

				S. C. Goodwin, J. B. Spies, R. Worthington-Kirsch, E. Peterson, G. Pron, S. Li, E. R. Myers, and for the Fibroid Registry for Outcomes Data (FIBROI Uterine Artery Embolization for Treatment of Leiomyomata: Long-Term Outcomes From the FIBROID Registry Obstet. Gynecol., January 1, 2008; 111(1): 22 - 33. [Abstract] [Full Text] [PDF]

				J. B. Spies, E. R. Myers, R. Worthington-Kirsch, J. Mulgund, S. Goodwin, M. Mauro, and for the FIBROID Registry Investigators The FIBROID Registry: Symptom and Quality-of-Life Status 1 Year After Therapy Obstet. Gynecol., December 1, 2005; 106(6): 1309 - 1318. [Abstract] [Full Text] [PDF]