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Obstetrics & Gynecology 2005;105:1309-1318
© 2005 by The American College of Obstetricians and Gynecologists
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ORIGINAL RESEARCH

Sexual Functioning After Total Compared With Supracervical Hysterectomy: A Randomized Trial

Miriam Kuppermann, PhD, MPH, Robert L. Summitt, Jr, MD, R. Edward Varner, MD, S. Gene McNeeley, MD, Deborah Goodman-Gruen, MD, PhD, Lee A. Learman, MD, PhD, Christine C. Ireland, MPH, Eric Vittinghoff, PhD, Feng Lin, MS, Holly E. Richter, PhD, MD, Jonathan Showstack, PhD, MPH, Stephen B. Hulley, MD, MPH, A. Eugene Washington, MD, MSc for the Total or Supracervical Hysterectomy (TOSH) Research Group*

From the Departments of Obstetrics, Gynecology & Reproductive Sciences, Epidemiology & Biostatistics, and Institute for Health Policy Studies, University of California, San Francisco, San Francisco, California; University of Tennessee, Memphis, Tennessee; Wayne State University, Detroit, Michigan; University of California, San Diego, La Jolla, California; University of Alabama, Birmingham, Alabama.

OBJECTIVE: To compare sexual functioning and health-related quality-of-life outcomes of total abdominal hysterectomy (TAH) and supracervical hysterectomy (SCH) among women with symptomatic uterine leiomyomata or abnormal uterine bleeding refractory to hormonal management.

METHODS: We randomly assigned 135 women scheduled to undergo abdominal hysterectomy in 4 U.S. clinical centers to either a total or supracervical procedure. The primary outcome was sexual functioning at 2 years, as assessed by the Medical Outcomes Study Sexual Problems Scale. Secondary outcomes included specific aspects of sexual functioning and health-related quality-of-life at 6 months and 2 years.

RESULTS: Sexual problems improved dramatically in both randomized groups during the first 6 months and plateaued by 1 year. Health-related quality-of-life scores also improved in both groups. At 2 years, both groups reported few problems with sexual functioning (mean score on the Sexual Problems Scale for SCH group 82, TAH group 80, on a 0-to-100 scale with 100 indicating an absence of problems; difference = +2, 95% confidence interval –8 to + 11), and there were no significant differences between groups.

CONCLUSION: Supracervical and total abdominal hysterectomy result in similar sexual functioning and health-related quality of life during 2 years of follow-up. This information can help guide physicians as they discuss surgical options with their patients.

LEVEL OF EVIDENCE: I




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