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Obstetrics & Gynecology 2005;105:1221-1223
© 2005 by The American College of Obstetricians and Gynecologists
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Right arrow Medical complications of pregnancy

CASE REPORTS

Severe Graves’ Ophthalmopathy in Pregnancy

Irene P. Stafford, MD, Gary A. Dildy, III, MD and Joseph M. Miller, Jr, MD

Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center; New Orleans, Louisiana

BACKGROUND: Thyroid ophthalmopathy is a rare extrathyroidal complication most commonly associated with Graves’ disease. The disease course ranges from mild to severe, with severe cases resulting in major visual impairment and facial disfigurement.

CASE: A 22-year-old primigravida developed severe thyroid ophthalmopathy during pregnancy, requiring high-dose steroids and surgical orbital wall decompression to restore visual acuity.

CONCLUSION: Severe thyroid ophthalmopathy can occur in the euthyroid pregnant patient. Corticosteroid therapy and surgical intervention may be required during pregnancy in this clinical scenario.






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