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Obstetrics & Gynecology 2004;104:801-804
© 2004 by The American College of Obstetricians and Gynecologists
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ORIGINAL RESEARCH

Antral Follicle Count and Serum Follicle-Stimulating Hormone Levels to Assess Functional Ovarian Age

Gregory E. Chow, MD, Amy R. Criniti, MD and Michael R. Soules, MD

From the Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington.

OBJECTIVE: The objective of this study was 2-fold. The first was to estimate side-to-side variation in antral follicle counts. The second was to determine whether basal follicle-stimulating hormone levels on days 2, 3, and 4 of the same menstrual cycle are significantly different.

METHODS: Forty-one patients between the ages of 20 and 42 years undergoing monitoring for in vitro fertilization-embryo transfer were evaluated ultrasonographically for antral follicle number. The antral follicle counts were determined for each ovary by experienced ultrasonographers at the time of suppression check ultrasonography. In a separate study, 62 normal subjects (ages 20–25 and 40–45 years) underwent serial sequential serum follicle-stimulating hormone determinations on days 2–4 of the menstrual cycle, and these levels were compared.

RESULTS: There was no significant difference between right and left antral follicle counts (P = .30). Serial follicle-stimulating hormone values were not significantly different on days 2, 3, or 4 of the menstrual cycle (P = .22).

CONCLUSION: There is no significant difference between right-sided and left-sided antral follicle counts within the same individual. In turn, there is no significant difference in serial follicle-stimulating hormone levels on days 2, 3, or 4 of the menstrual cycle.

LEVEL OF EVIDENCE: III






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