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Obstetrics & Gynecology 2004;104:527-530
© 2004 by The American College of Obstetricians and Gynecologists
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ORIGINAL RESEARCH

Perinatal Outcome of Pregnancies Complicated by Placenta Accreta

Yuval Gielchinsky, MD, David Mankuta, MD, Nathan Rojansky, MD, Neri Laufer, MD, Ilan Gielchinsky, BMedSc and Yossef Ezra, MD

From the Department of Obstetrics and Gynecology, Hadassah Medical Center, The Hebrew University, Jerusalem, Israel.

Address reprint requests to: Yuval Gielchinsky, MD, Department of Obstetrics and Gynecology Hadassah Hebrew University Medical Center, Ein Kerem P.O. Box 12000, Jerusalem, 91120, Israel; e-mail: yuvalgi{at}attglobal.net.

OBJECTIVE: The purpose of the study was to characterize the perinatal outcome of pregnancies complicated by placenta accreta.

METHODS: We conducted a case-control analysis of all deliveries between the years 1990 and 2000 that were complicated by placenta accreta. Perinatal variables included in the analysis were gestational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P < .05 was considered significant.

RESULTS: The study encompassed 34,450 deliveries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compared with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preterm deliveries (10.7% versus 1%, P < .001, odds ratio 12.1, 95% confidence interval 3.7–39.9) and small-for-gestational-age babies (27.3% versus 14%, P < .001, odds ratio 5.05, 95% confidence interval 1.46–3.28).

CONCLUSION: Pregnancies complicated by placenta accreta are at increased risk for perinatal adverse outcome. We speculate that these findings may arise from pathological implantation of the placenta, resulting in interference with normal fetal growth.

LEVEL OF EVIDENCE: II-2




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D. DiGiacinto and A. Hildebrand
Placenta Accreta.
Radiol. Technol., November 1, 2006; 78(2): 165 - 168.
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