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Obstetrics & Gynecology 2004;103:1073-1075
© 2004 by The American College of Obstetricians and Gynecologists
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CASE REPORTS

A Life-Threatening Event: Uterine Cervical Arteriovenous Malformation

Lior Lowenstein, MD*, Ido Solt, MD*, Michael Deutsch, MD*, Hedviga Kerner, MD{dagger} and Amnon Amit, MD*

*Department of Obstetrics and Gynecology and {dagger}Department of Pathology, Rambam Medical Center and the Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel

Address reprint requests to: Lior Lowenstein, MD, Department of Obstetrics and Gynecology, Rambam Medical Center, POB 9602, Haifa 31096 Israel; e-mail: l_lior{at}rambam.health.gov.il.

BACKGROUND: Uterine cervical arteriovenous malformation is a rare cause of vaginal bleeding.

CASE: A 32-year-old multigravida presented with severe vaginal bleeding originating in the cervix, which resulted in a hypovolemic shock. Attempts to control the bleeding included hysterectomy, pelvic arterial embolization, and upper vaginectomy. Each proved unsuccessful. Histopathologic examination revealed an arteriovenous malformation. Despite local packing, suturing of the vault area, and brachytherapy to the vaginal vault, bleeding persisted. Treatment with GnRH agonist and tranexamic acid stopped the bleeding.

CONCLUSION: Severe vaginal bleeding can be the result of cervical arteriovenous malformation, and GnRH agonist may be used for treatment.




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M. Morikawa, T. Yamada, H. Yamada, and H. Minakami
Effect of gonadotropin-releasing hormone agonist on a uterine arteriovenous malformation.
Obstet. Gynecol., September 1, 2006; 108(3 Pt 2): 751 - 753.
[Abstract] [Full Text] [PDF]


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