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ORIGINAL RESEARCH |
From the Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco; and Department of Obstetrics and Gynecology, California Pacific Medical Center, San Francisco, California.
Address reprint requests to: Aaron B. Caughey, MD, MPP, MPH, University of California, San Francisco, Department of Obstetrics and Gynecology, 505 Parnassus Avenue, Box 0856, San Francisco, CA 94143; e-mail: abcmd{at}uclink.berkeley.edu.
OBJECTIVE: To estimate when rates of pregnancy complications increase beyond 37 weeks of gestation.
METHODS: We designed a retrospective, cohort study of all women delivered beyond 37 weeks of gestational age from 1992 to 2002 at a single community hospital. Rates of perinatal complications by gestational age were analyzed with both bivariate and multivariable analyses. Statistical significance was designated by P < .05.
RESULTS: Among the 45,673 women who delivered at 37 completed weeks and beyond, the rates of meconium and macrosomia increased beyond 38 weeks of gestation (P < .001), the rates of operative vaginal delivery, chorioamnionitis, and endomyometritis all increased beyond 40 weeks of gestation (P < .001), and rates of intrauterine fetal death and cesarean delivery increased beyond 41 weeks of gestation (P < .001).
CONCLUSION: Risks to both mother and infant increase as pregnancy progresses beyond 40 weeks of gestation.
LEVEL OF EVIDENCE: II-3
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