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An Unusual Presentation of Struma Ovarii Mimicking a Malignant Process

The Division of Gynecologic Oncology, The Chao Family Comprehensive Cancer Center, University of California, Irvine Medical Center, Orange, California

Address reprint requests to: Michael L. Berman, MD, The Chao Family Comprehensive Cancer Center, The Division of Gynecologic Oncology, University of California, Irvine Medical Center, 101 The City Drive, Orange, CA 92868; E-mail: mberman{at}uci.edu.

ABSTRACT

BACKGROUND: Struma ovarii is a rare form of ovarian neoplasm, composed entirely or predominantly of thyroid tissue. This tumor is generally benign, although malignant transformation has been reported.

CASE: We report an unusual presentation of a postmenopausal woman with benign struma ovarii associated with a large amount of ascites, a markedly elevated CA 125 serum level, and a large complex pelvic mass thereby mimicking an ovarian cancer.

CONCLUSION: This case serves to remind clinicians that clinical features highly suspicious for ovarian cancer do not necessarily confirm a malignancy.